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Laboratory Ion Exchange Chromatography

Separating compounds based on net surface charge

Ion Exchange Chromatography Solutions for Every Application

Ion exchange chromatography separates compounds based on net surface charge. Molecules are classified as either anions (having a negative charge) or cations (having a positive charge). Some molecules (e.g., proteins) may have both an anionic and cationic group. A positively-charged support (anion exchanger) will bind a compound with an overall negative charge. Conversely, a negatively-charged support (cation exchanger) will bind a compound with an overall positive charge. 

 

Ion exchange matrices can be further categorized as either strong or weak. Strong ion exchange matrices are charged (ionized) across a wide range of pH levels. Weak ion exchange matrices are ionized within a narrower pH range. 

 

Pall offers ion exchange resins and membranes. In many areas, chromatography resins are the media of choice for chromatography applications, but in some cases where resin-based methods have limitations (e.g., purification of viruses or large molecules) membranes have proven to be a robust, scalable, and economic alternative. Membranes perform well in such applications because of their faster flow rates compared to resins.

 

 

ion-exchange-filters

Acrodisc® Units with Mustang® Q and S Membranes

Disposable Chromatography Units with High Binding Capacities and Fast Flow Rates
Disposable Chromatography Units with High Binding Capacities and Fast Flow Rates
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Acrodisc® Units with Mustang® E Membrane

Remove Endotoxin from Water, Buffer, Neutral Sugars, and Certain Biological Solutions
Remove Endotoxin from Water, Buffer, Neutral Sugars, and Certain Biological Solutions
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AcroPrep™ Advance 96-Well Filter Plates for Protein Purification

Versatile Format for Multiple Purification Strategies
Versatile Format for Multiple Purification Strategies
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